Combination therapy with radiation, mitomycin C, and 5-fluorouracil in EMT6 tumors
โ Scribed by Sara Rockwell
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 913 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0360-3016
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The effectiveness of MFC (mitomycin C, 5-fluorouracil and cytosine arabinoside) therapy for nonresectable cancers and cancers recurring after surgery was investigated in 60 patients with solid cancers aged 26 to 69 years. Treatment was effective in 28 patients (47%) including seven (12%) who showed
Twenty-nine patients with carcinoma of the esophagus were treated with 5-fluorouracil(5-FU) (1000 mg/ m2/d as a continuous intravenous [IV] infusion on days 1 through 4), cisplatin (100 mg/m2 IV on day I), mitomycin C (10 mg/m2 IV on day I), and concurrent radiation therapy (4500 cCy/4.5 wk). If no