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Combination therapy with methylprednisolone and brain-derived neurotrophic factor for acute spinal cord injury


Book ID
119615911
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
39 KB
Volume
2
Category
Article
ISSN
1529-9430

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PEGylation of brain-derived neurotrophic
✍ Ryan G. Soderquist; Erin D. Milligan; Evan M. Sloane; Jacqueline A. Harrison; Kl πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 241 KB

## Abstract Brain‐derived neurotrophic factor (BDNF) was covalently attached to polyethylene glycol (PEG) in order to enhance delivery to the spinal cord via the cerebrospinal fluid (intrathecal administration). By varying reaction conditions, mixtures of BDNF covalently attached to one (primary),