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Combination therapy with bone marrow stromal cells and FK506 enhanced amelioration of ischemic brain damage in rats

✍ Scribed by Satoshi Suda; Kuniko Shimazaki; Masayuki Ueda; Toshiki Inaba; Nobuo Kamiya; Ken-ichiro Katsura; Yasuo Katayama

Book ID
116720002
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
502 KB
Volume
89
Category
Article
ISSN
0024-3205

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## Abstract The glial scar, a primarily astrocytic structure bordering the infarct tissue inhibits axonal regeneration after stroke. Neurocan, an axonal extension inhibitory molecule, is up‐regulated in the scar region after stroke. Bone marrow stromal cells (BMSCs) reduce the thickness of glial sc