✦ LIBER ✦
Combination therapy: Photochemotherapy; electric current; and ionizing radiation. Different combinations studied in a WiDr human colon adenocarcinoma cell line
✍ Scribed by Liwei Ma; Vladimir Iani; Johan Moan
- Publisher
- Elsevier Science
- Year
- 1993
- Tongue
- English
- Weight
- 583 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1011-1344
No coin nor oath required. For personal study only.
✦ Synopsis
The interactions of pairs of the modalities Photofrin II-sensitized photochemotherapy (PCT), ionizing radiation and an electric current were investigated by the colony formation assay in WiDr cells, a human colon adenocarcinoma cell line. When the cells were treated simultaneously with PCT and an electric current, a slightly synergistic effect was observed at low exposures (surviving fraction -0.1) while a seemingly antagonistic effect was found at higher exposures.
The same was found to be true for the combinations of PCT plus ionizing radiation and ionizing radiation plus electric current.