Combination therapy of E-antigen-negative/virus-DNA-positive (precore mutant) chronic hepatitis B with famciclovir or lamivudine and interferon (IFN) alfa-2a
✍ Scribed by I. Schiefke; U. Oesen; G. Etzrodt; M. Wiedmann; U.G. Liebert; J. Moessner; F. Berr
- Book ID
- 119526427
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 107 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0168-8278
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This placebo controlled, double-blind study evaluated the efficacy and safety of lamivudine in patients with hepatitis B e antigen (HBeAg)-negative/hepatitis B virus (HBV) DNA-positive chronic hepatitis B. Patients were randomized to receive 100 mg lamivudine orally once daily for 52 weeks (n ؍ 60
ment for anti-HBe-positive chronic hepatitis. The benefit It has recently been shown that thymosin-a 1 (T-a 1 ), a of this agent in producing long-term inhibition of HBV synthetic polypeptide of thymic origin, is able to proreplication must be confirmed by future trials. (HEPAmote disease remission