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Combination of thiol antioxidant Silibinin with Brostallicin is associated with increase in the anti-apoptotic protein Bcl-2 and decrease in caspase 3 activity

✍ Scribed by Sim-Hwee Pook; Chee-Keong Toh; Ratha Mahendran

Book ID: 116333885
Publisher: Elsevier Science
Year: 2006
Tongue: English
Weight: 156 KB
Volume: 238
Category: Article
ISSN: 0304-3835
DOI: 10.1016/j.canlet.2005.07.002

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## Abstract Alzheimer's disease (AD) is the most common form of dementia and is pathologically characterized by senile plaques, neurofibrillary tangles, synaptic disruption and loss, and progressive neuronal deficits. The exact mechanism(s) of AD pathogenesis largely remain unknown. With advances i