Combination of the proliferation marker cyclin A, histological grade, and estrogen receptor status in a new variable with high prognostic impact in breast cancer

Loss of 16q in high grade breast cancer

Loss of 16q in high grade breast cancer is associated with estrogen receptor status: Evidence for progression in tumors with a luminal phenotype?

✍ Rachael Natrajan; Maryou B. K. Lambros; Felipe C. Geyer; Caterina Marchio; David 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 883 KB

## Abstract Loss of the long arm of chromosome 16 (16q) is observed in the vast majority of low grade/grade I (GI) invasive ductal carcinomas of no special type (IDC‐NSTs), whereas this event is uncommonly seen in high grade/grade III (GIII) IDC‐NSTs. Together with data on the pathology and genetic