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Combination of temozolomide (TMZ) and radiotherapy (RT) versus radiotherapy (RT) alone in newly diagnosed glioblastoma multiforme (GBM): A randomized phase II study

✍ Scribed by H. Athanassiou; M. Synodinou; E. Maragoudakis; M. Paraskevaidis; C. Verigos; D. Misailidou; D. Antonadou; G. Sarris; K. Beroukas; P. Karageorgis

Book ID: 108148460
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 32 KB
Volume: 60
Category: Article
ISSN: 0360-3016
DOI: 10.1016/j.ijrobp.2004.06.082

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## Abstract ## BACKGROUND Currently, the survival of patients age > 70 years with glioblastoma multiforme (GBM) ranges from 4 months to 6 months, although radiotherapy and/or chemotherapy may prolong survival in certain subgroups. Temozolomide is an oral chemotherapeutic agent with efficacy agains

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