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Combination of renal agenesis with respiratory and alimentary tract atresia results in normal lung development

✍ Scribed by McLeod, D.R. ;Akierman, A. ;Trevenen, C.


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
145 KB
Volume
102
Category
Article
ISSN
0148-7299

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✦ Synopsis


The VACTERL complex comprises renal agenesis and atresias of the alimentary and respiratory tracts. We report on a case with this combination causing severe oligohydramnios but with normal lung development. The likely protective mechanism for pulmonary development was an increase in alveolar pressure and reduced alveolar ¯uid loss due to the esophageal-tracheal malformation. This suggests the possible treatment of oligohydramnios by tracheal occlusion.