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Combination of quercetin with radiotherapy enhances tumor radiosensitivity in vitro and in vivo

✍ Scribed by Chenghe Lin; Yan Yu; Hong-guan Zhao; Aimin Yang; Hong Yan; Yali Cui

Book ID
116855639
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
511 KB
Volume
104
Category
Article
ISSN
0167-8140

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## Abstract Valproic acid (VA) is a well‐tolerated drug used to treat seizure disorders and has recently been shown to inhibit histone deacetylase (HDAC). Because HDAC modulates chromatin structure and gene expression, parameters considered to influence radioresponse, we investigated the effects of