## BACKGROUND. The antitubule agent paclitaxel causes a cell cycle blockage in the most radiosensitive part of the cell cycle, the GJM phase. The possible radiosensitizing effect of paclitaxel was tested in four vulvar (UM-SCV-lA, UM-SCV-lB, UM-SCV-2, and UM-SCV-4) squamous cell carcinoma (SCC) ce
✦ LIBER ✦
Combination of paclitaxel and radiation: genotoxicity in vitro in four mammalian cell lines
✍ Scribed by Verena K Preisler; Daniela Wück; Helga Stopper
- Book ID
- 118578971
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 78 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0304-3835
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## Abstract Concurrent paclitaxel and radiation has given promising results in the treatment of a variety of solid tumors. We wanted to test the efficacy of this combination for vulvar carcinoma, which currently has a poor outcome in advanced stages. The radiation sensitivity, sublethal damage repa
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