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Combination of methylprednisolone and minocycline synergistically improves experimental autoimmune encephalomyelitis in C57 BL/6 mice

✍ Scribed by Xiaohong Chen; Rongbiao Pi; Mei Liu; Xiaomeng Ma; Ying Jiang; Yingying Liu; Xuexuan Mao; Xueqiang Hu

Book ID: 113730693
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 788 KB
Volume: 226
Category: Article
ISSN: 0165-5728
DOI: 10.1016/j.jneuroim.2010.05.039

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## Abstract Multiple sclerosis (MS) is an autoimmune, demyelinating disease of the central nervous system (CNS). Like MS, the animal model experimental autoimmune encephalomyelitis (EAE) is characterized by CNS inflammation and demyelination and can follow a relapsing–remitting (RR) or chronic (CH)