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COMBINATION OF FIVE SNPs PREDICTS INDIVIDUAL RISK FOR PROSTATE CANCER

โœ Scribed by Xu, Jianfeng; Zheng, Siqun L; Wiklund, Fredrik; Sun, Jielin; Chang, Bao-Li; Adami, Hans-Olov; Partin, Alan W; Walsh, Patrick C; Gronberg, Henrik; Isaacs, William B


Book ID
123228456
Publisher
Lippincott Williams and Wilkins
Year
2008
Tongue
English
Weight
244 KB
Volume
179
Category
Article
ISSN
0022-5347

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Evaluation of polygenic risk scores for
โœ Mitchell J. Machiela; Chia-Yen Chen; Constance Chen; Stephen J. Chanock; David J ๐Ÿ“‚ Article ๐Ÿ“… 2011 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 134 KB ๐Ÿ‘ 1 views

Recently, polygenic risk scores (PRS) have been shown to be associated with certain complex diseases. The approach has been based on the contribution of counting multiple alleles associated with disease across independent loci, without requiring compelling evidence that every locus had already achie