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Combination of cisplatin/S-1 in the treatment of patients with advanced gastric or gastroesophageal adenocarcinoma: Results of noninferiority and safety analyses compared with cisplatin/5-fluorouracil in the First-Line Advanced Gastric Cancer Study

✍ Scribed by Ajani, J.A.; Buyse, M.; Lichinitser, M.; Gorbunova, V.; Bodoky, G.; Douillard, J.Y.; Cascinu, S.; Heinemann, V.; Zaucha, R.; Carrato, A.; Ferry, D.; Moiseyenko, V.

Book ID
121362399
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
502 KB
Volume
49
Category
Article
ISSN
0959-8049

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## Abstract A phase III trial of S‐1 plus cisplatin (SP) __versus__ S‐1 alone, for first‐line treatment of advanced gastric cancer (SPIRITS trial), has shown that overall survival was better in patients treated with SP than with S‐1 alone. In the present retrospective biomarker study, we aimed to d