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Combination of chemotherapy and recombinant alpha-interferon in advanced non-small cell lung cancer: Multicentric randomized FONICAP trial report

✍ Scribed by Andrea Ardizzoni; Franco Salvati; Riccardo Rosso; Paolo Bruzzi; Alessandra Rubagotti; Maria Cristina Pennucci; Gabriella Lucia Mariani; Filippo De Marinis; Giovanni Pallotta; Antonio Antilli; Anna Maria Cruciani; Massimo Rinaldi; Riccardo Tonachella; Marina Fioretti; Santi Barbera; Ennio Mantellini; Enzo Soresi; Gisella Pastorino; Mario Belli; Giuseppe Ferrara; Marco Venturini; Giorgio Scagliotti; Leonardo Santi

Publisher: John Wiley and Sons
Year: 1993
Tongue: English
Weight: 647 KB
Volume: 72
Category: Article
ISSN: 0008-543X
DOI: 10.1002/1097-0142(19931115)72:10<2929::aid-cncr2820721012>3.0.co;2-x

No coin nor oath required. For personal study only.

✦ Synopsis

Background. Preclinical data suggested that alphainterferon (IFN) may potentiate chemotherapy cytotoxicity.

Methods. A prospective multicentric randomized trial was initiated to assess the clinical benefit of adding This work was conducted by the Italian Lung Cancer Task Force (FONICAP), which carried out the trial with the following institutions: Istituto Nazionale per la Ricerca sul Cancro (R.

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