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Combination of allyl protection and HYCRAMTM-linker technology for the synthesis of peptides with problematical amino acids and sequences

✍ Scribed by Rita Gothe; Lydia Seyfarth; Christina Schumann; Inge Agricola; Siegmund Reissmann; Axel Lifferth; Christian Birr; Magarita Pavlovna Filatova; Alexander Kritsky; Vladimir Kibirev


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
92 KB
Volume
341
Category
Article
ISSN
1615-4150

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Papain catalyzed synthesis of glyceryl e
✍ Yuri V. Mitin; Karin Braun; Peter Kuhl πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 113 KB πŸ‘ 1 views

Papain catalyzed synthesis of glyceryl esters of BOC(Z)-protected amino acids and peptides was performed at 40-50Β°C in a 50 molar excess of glycerol. Equilibrium was achieved in 6-7 h. The maximal yield of esters (50-70%) was obtained at 10% of water and pH 3.2-3.4. A lower water concentration resul