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Combination Finasteride and Flutamide in Advanced Carcinoma of the Prostate: Effective Therapy with Minimal Side Effects

✍ Scribed by Fleshner, Neil E.; Trachtenberg, John

Book ID
122067386
Publisher
Lippincott Williams and Wilkins
Year
1995
Tongue
English
Weight
616 KB
Volume
154
Category
Article
ISSN
0022-5347

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## BACKGROUND. It was very reasonable to consider that the combination of the 5␣reductase, finasteride, and a pure antiandrogen such as flutamide should provide an effective form of maximal androgen blockade (MAB). Finasteride decreases intraprostatic levels of 5␣dihydrotestosterone (DHT), and the