Combination chemotherapy with mitomycin C and cisplatin for advanced gastric cancer with multiple liver metastases
โ Scribed by Yoshiro Saikawa; Tetsuro Kubota; Toshiharu Furukawa; Koichiro Kumai; Keiichi Yoshino; Kyuya Ishibiki; Masaki Kitajima
- Book ID
- 112580638
- Publisher
- Springer
- Year
- 1994
- Tongue
- English
- Weight
- 587 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1436-2813
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A 55-year-old female, in which an unresectable Borrmann II-type gastric cancer (moderately differentiated adenocarcinoma) extending from vicinity of the cardia to the lower portion of the corpus, with direct invasion into the pancreas and extensive lymph node metastases, confirmed by laparotomy, was
A new combined cancer chemotherapy regimen of mitomycin C (MMC) and cisplatin (DDP) showed synergistic antitumor activity against human gastric cancer xenografts St-40 and SC-1-NU in BALB/c nu/nu mice. The drugs were administered intraperitoneally at doses of 2 or 4 mg/kg for MMC and 3 or 6 mg/kg fo