Combination chemotherapy: The antagonism of methotrexate and cytosine arabinoside
โ Scribed by M.H.N. Tattersall; K.R. Harrap
- Book ID
- 114012772
- Publisher
- Elsevier Science
- Year
- 1973
- Weight
- 217 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0014-2964
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Twenty-three adult patients with meningeal involvement by a variety of malignancies were treated with the intra-Ommaya combination of methotrexate, hydrocortisone, cytosine arabinoside, and thio-TEPA. Whole brain irradiation was also administered to most patients who had not previously received it.
Thirty patients with acute granulocytic leukemia were treated with ARA-C (100 mg/m2 IV during 5 days) and RBD (100 mg/m\*/day during 3 days). Twentytwo patients with AML and eight with APML were treated. The drugs always induced severe pancytopenia lasting an average of 18 days. Sixteen patients ach