๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Combination chemotherapy pneumonitis: A case report of possible synergistic toxicity

โœ Scribed by Goedert, James J. ;Smith, Frederick P. ;Tsou, Edward ;Weiss, Raymond B.

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
296 KB
Volume
11
Category
Article
ISSN
0098-1532

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โœฆ Synopsis

A woman with pancreatic cancer developed acute interstitial infiltrates while receiving modest doses of two potential pulmonary toxins, mitomycin-C and chlorozotocin. Chemotherapy pneumonitis, confirmed by lung biopsy, responded dramatically to prednisone with negligible sequelae. Comparison with the doses in other reported cases suggested additive or synergistic toxicity between these two alkylating agents.

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