During a 3-year period 39 evaluable patients with stage III and IV non-Hodgkin's lymphomas and unfavorable histologies were treated with a unique chemotherapeutic regimen based on a modified CHOP combination to which was added the nitrosourea, CCNU. Complete response was observed in six of 15 (40%)
Combination chemotherapy for advanced non-Hodgkin's lymphoma of unfavourable histology
β Scribed by T. A. Lister; M. H. Cullen; R. B. Brearley; M. E. J. Beard; A. G. Stansfeld; J. M. A. Whitehouse; P. F. M. Wrigley; J. M. Ford; J. S. Malpas; D. Crowther
- Book ID
- 112285976
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 459 KB
- Volume
- 1
- Category
- Article
- ISSN
- 0344-5704
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Twenty patients with relapsed or refractory, intermediate or high grade non Hodgkin's lymphoma were treated with a combination of CCNU and vinblastine. Complete responses occurred in four patients (20 per cent), partial responses in eight (40 per cent), for an overall response rate of 60 per cent. T
## Abstract Between October 1985 and October 1989, 75 previously untreated patients with stage III and IV non Hodgkin's lymphoma, large cell type, were treated with an alternating weekly chemotherapy regimen including the following drugs: week 1: Doxorubicin, vincristine, cyclophosphamide, bleomyci