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Combination chemotherapy for adrenocortical carcinoma

✍ Scribed by Kathryn Senior

Book ID
117786153
Publisher
The Lancet
Year
2012
Tongue
English
Weight
66 KB
Volume
13
Category
Article
ISSN
1470-2045

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## Abstract ## BACKGROUND Adrenocortical carcinoma (ACC) is rare, nearly always fatal, and to the authors' knowledge has few nonsurgical treatment options. Based on in vitro studies demonstrating the efficacy of mitotane as a P‐glycoprotein (Pgp) antagonist, and expression of high levels of Pgp in