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Columbamine, the central intermediate in the late stages of protoberberine biosynthesis

โœ Scribed by M. Rueffer; M.H. Zenk


Publisher
Elsevier Science
Year
1986
Tongue
French
Weight
133 KB
Volume
27
Category
Article
ISSN
0040-4039

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Synthesis of a Central Intermediate in t
โœ Mรผller, Thomas ;Schmidt, Richard R. ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 943 KB

## Abstract The synthesis of disodium (6โ€deoxyโ€ฮฑโ€Dโ€__ribo__โ€hexopyranโ€3โ€ulosyl) (2โ€ฒโ€deoxythymidinโ€5โ€ฒโ€yl) diphosphate (1) is described. To this end, Dโ€glucose is transformed into known furanose derivative 2 possessing a 3โ€__C__โ€methylene group as latent functionality for 3โ€ulose generation. From 2,