Retrospective studies of the relationship between perioperative blood transfusion and colorectal cancer recurrence are reviewed. Perioperative blood transfusion was associated with preoperative anemia, operations for rectal carcinoma, presence of tumor in the right colon, prolonged procedures, and c
Colorectal cancer recurrence and perioperative blood transfusions: A critical reappraisal
โ Scribed by Olivier R. C. Busch; Richard L Marquet; WIM C. J. Hop; Prof. Dr. Johannes Jeekel
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 513 KB
- Volume
- 10
- Category
- Article
- ISSN
- 8756-0437
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โฆ Synopsis
The last 2 decades the immunomodulatory effect of blood transfusions has been investigated intensively. The effect of blood transfusions on the prognosis of colorectal cancer patients is reviewed in this paper. We made an evaluation of the material from animal and from clinical studies present in the literature. The results from clinical randomized trials dealing with this subject, which have been published recently, are discussed as well.
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Abstract The aim of the present study was to examine the outcome of 517 patients undergoing curative surgery for colonic and rectal cancer, and to compare the recurrence and mortality rates in transfused and non-transfused groups of patients. The two groups were evenly matched for age, sex, Dukes' s
An adverse relationship between perioperative blood transfusions and the risk of subsequent recurrence of cancer was reported recently. We reviewed retrospectively the records of 171 patients who received initial therapy for colorectal adenocarcinoma from 1977 to 1979 at the Virginia Mason Medical C