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Colorectal cancer prognosis and expression of exon-v6-containing CD44 proteins

✍ Scribed by J.-W.R. Mulder; Miguel Sewnath; Gja Offerhaus; St Pals; J. Oosting; Pm Kruyt; Wf Weidema; Ca Seldenrijk

Book ID
118554237
Publisher
The Lancet
Year
1994
Tongue
English
Weight
433 KB
Volume
344
Category
Article
ISSN
0140-6736

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CD44 is a cell surface glycoprotein with a number of isoforms generated by alternative splicing of ten 'variant' exons in humans. Variant exon 6-containing isoforms of CD44 (CD44v6) have been implicated in the metastatic potential of rat carcinoma cell lines. Human homologues of CD44v6 are expressed