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Colonic lymphoma complicating ulcerative colitis

✍ Scribed by P. Renton; A. J. Blackshaw

Publisher
John Wiley and Sons
Year
1976
Tongue
English
Weight
470 KB
Volume
63
Category
Article
ISSN
0007-1323

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A rat model for human ulcerative colitis (UC) has been developed by using 1-hydroxyanthraquinone (1-HA) to cause severe inflammation of colonic mucosa. 1-HA also has synergistic effects on the carcinogenicity of methylazoxymethanol (MAM) acetate in the rat colon. In this study, four adenomas and 16