Background: Several lines of evidence have shown that helminthiasis can significantly reduce disease severity in animal models of intestinal inflammation, airway inflammation/hyperreactivity, diabetes, and multiple sclerosis. Identification and characterization of helminth-derived immunomodulatory m
Colonic antioxidant status in dextran sulfate-induced colitis in mice
β Scribed by Anneke C. Blackburn; William F. Doe; Dr. Gary D. Buffinton
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 624 KB
- Volume
- 3
- Category
- Article
- ISSN
- 1078-0998
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
P-glycoprotein (P-gp), the product of the multiple drug resistance (mdr) gene, can actively pump toxic drugs out of cells, but its pathophysiologic role is not yet fully understood. In this study, we examined the expression of P-gp in dextran sodium sulfate (DSS)-induced colitis in mice. Eight-week-
## Abstract **Scope:** Dietary supplementation of nβ3 PUFAs, containing docosahexaenoic acid (DHA), modulates the symptoms of colitis. Hence, we investigated the effects of oral administration of pure DHA and the therapeutic agent sulfasalazine (SAL) on chemically induced colitis in mice, and analy
## Background: Dextran sodium sulfate (dss) induces submucosal arteriolar constriction that reduces blood flow to the intestine, and the relevance of this decrease in flow needs further investigation. in the present study we examined the effects of a vasoconstrictor (pseudoephedrine) and a vasodila
## Abstract The mouse model for familial adenomatous polyposis, __Apc__^__Min__/+^ mouse, contains a truncating mutation in the __Apc__ gene and spontaneously develops numerous adenomas in the small intestine but few in the large bowel. Our study investigated whether dextran sodium sulfate (DSS) tr
## Background: In this study we determined the consequence of the absence of each tnf receptor, tnfr1 or tnfr2, in the dextran sulfate sodium (dss) model of colitis. ## Methods: Wildtype (wt), tnfr1(-/-) and tnfr2(-/-) mice were fed 3% w/v dss in drinking water for 5 days followed by 2 (day 7) or