Acetylcholine has important epigenetic roles in the developing retina. In this study, cells that expressed choline acetyltransferase (ChAT), the enzyme that synthesizes acetylcholine, were investigated in embryonic, postnatal, and adult turtle retinas by using immunofluorescence histochemistry. ChAT
Colocalization of choline acetyltransferase and ?-aminobutyric acid in the developing and adult turtle retinas
β Scribed by Nguyen, Lynette T.; Grzywacz, Norberto M.
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 998 KB
- Volume
- 420
- Category
- Article
- ISSN
- 0021-9967
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β¦ Synopsis
Acetylcholine and β₯ -aminobutyric acid (GABA) are putative neurotransmitters in the adult vertebrate retina. In this study, cells that coexpress choline acetyltransferase (ChAT) and GABA or glutamic acid decarboxylase (GAD) were investigated in turtle retinas from stage 14 (S14) to adulthood by using a double-labeling immunofluorescence technique. ChAT immunoreactivity was observed at S15 and included not only the presumptive starburst cholinergic amacrine cells but also a population in the ganglion cell layer (GCL) that expressed ChAT transiently during the embryonic stages (see the accompanying
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## Abstract Immunoreactivity for the plasma membrane GABA transporter, GATβ3 (red), in a vertical section of adult mouse retina, with the MΓΌller glia identified with CRALBP antibodies (green) and bipolar cell and some MΓΌller cell somata with Chx10 antibodies (blue). J. Comp. Neurol. 512:6β26, 2009.
## Abstract Immunoreactivity for the plasma membrane GABA transporter, GATβ3 (red), in a vertical section of adult mouse retina, with the MΓΌller glia identified with CRALBP antibodies (green) and bipolar cell and some MΓΌller cell somata with Chx10 antibodies (blue). J. Comp. Neurol. 512:6β26, 2009.
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