Colloquium C03: Modeling brain metabolism: challenges and controversies
β Scribed by S. Hutson
- Book ID
- 111195909
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 339 KB
- Volume
- 94
- Category
- Article
- ISSN
- 0022-3042
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In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis of the 13C labeling time courses obtained experimentally with a metabolic model. The present work reviews the ingredients nece
## Abstract We review the contribution of mathematical modeling of metabolic pathways to the study of the compartmentalization of brain energy metabolism between neurons and glia. We especially focus on the role of lactate in the relationship between glia and neurons and the possible presence of an