Collision-Induced consecutive dissociation reactions of the monocarboxylate anions generated from the dimethyl and diethyl esters of glutaric acid and its 3,3-dimethyl analogue
✍ Scribed by Wilfried P. M. Maas; Nico M. M. Nibbering
- Publisher
- John Wiley and Sons
- Year
- 1990
- Tongue
- English
- Weight
- 493 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1076-5174
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✦ Synopsis
The collision-induced dissociation reactions of the monocarboxylate anions, generated from the dimethyl and diethyl esters of glutaric acid and its 3,3-dimethyl analogue in a chemical ionization source, were studied as a function of the potential applied to the collision cell in combination with *H labelling experiments. It was shown that many of the product anions are formed in consecutive steps. The mechanisms associated with these steps appear to be initiated by a functional group interaction between the carboxylate anion and the ester group, 1,s hydrogen migrations both to the carboxylate anion and the uncharged ester group and charge remote fragmentation. In one of the collision-induced dissociation channels a methyl anion is generated as a granddaughter product anion, which contains the hydrogen atoms exclusively originating from positions 2 and 4 as shown by the applied 'H labelling.