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Collagen-induced arthritis in rats

✍ Scribed by John M Stuart; Michael A Cremer; Andrew H Kang; Alexander S Townes

Publisher: John Wiley and Sons
Year: 1979
Tongue: English
Weight: 1009 KB
Volume: 22
Category: Article
ISSN: 0004-3591
DOI: 10.1002/art.1780221205

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An experimental model of human autoimmune arthritis is produced by the intradermal injection of native heterologous or homologous collagen in rats (1,2). The collagen, which may be emulsified in either complete or incomplete Freund's adjuvant, induces a chronic polyarthritis. Plastic surgeons have r