Collagen cross-linking
β Scribed by S. Ricard-Blum; G. Ville
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- English
- Weight
- 479 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0020-711X
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π SIMILAR VOLUMES
Cross-linking of collagen-based biomaterials increases their strength and persistence in vivo. Recently, we described an efficient cross-linking process via the formation of acyl azide groups on methylated carboxyl groups of collagen using hydrazine and nitrous acid (referred to here as the hydrazin
## Abstract A 3D spongy collagen cryogel was prepared using DAS as the crossβlinker. FTIR and CD studies demonstrate that crosslinking is achieved through the reaction of the DAS aldehyde groups with the free amino groups in collagen without affecting the triple helix of collagen. SEM demonstrates