Adhesion to collagens by most cell types is mediated by the integrins a1b1 and a2b1. Both integrin a subunits belong to a group which is characterized by the presence of an I domain in the N-terminal half of the molecule, and this domain has been implicated in the ligand recognition. Since purified
Collagen binding α2β1and α1β1integrins play contrasting roles in regulation of Ets-1 expression in human liver myofibroblasts
✍ Scribed by Iya Znoyko; Maria Trojanowska; Adrian Reuben
- Book ID
- 106457859
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 880 KB
- Volume
- 282
- Category
- Article
- ISSN
- 0300-8177
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Grant sponsor: Association pour la Recherche sur le Cancer (ARC); Grant sponsor: Fondation Recherche et Partage (Caisse d'Epargne); Grant sponsor: Fonds de Recherche de la Socie ´te ´Nationale Franc ¸aise de Gastroente ´rologie.