Decreased collagen accumulation by a pro
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Kenji Fujiwara; Itsuro Ogata; Yasuhiko Ohta; Shigeki Hayashi; Shunji Mishiro; Ka
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Article
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1988
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John Wiley and Sons
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English
โ 461 KB
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Hepatic fibrosis was induced in rats by repeated i.p. injections of pig serum. The hepatic hydroxyproline content increased to 2.1 times the normal control level at 6 weeks and to 3.2 times at 10 weeks. When P-l894B, an inhibitor of prolyl hydroxylase, was administered, there was a dose-dependent in