Collaborative study of monoclonal antibodies to human IgG subclasses and allotypes
โ Scribed by F. Skvaril; R. Jefferis
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 52 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0167-5699
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## Abstract Six ฮฒโmicroglobulins were isolated from the urine of six patients with renal tubular dysfunction. Crossโreactivity between these ฮฒ โmicroglobulins and antigenic determinants of different IgG allotypes and subclasses was investigated. No evidence of crossโreactivity was found. Some hypot
Temperature-induced unfolding of three humanized IgG1 monoclonal antibodies and their Fab and Fc fragments was monitored by differential scanning calorimetry at neutral pH. With some exceptions, the thermogram of the intact antibody presents two peaks and the transition with the larger experimental