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Collaborated regulation of female-specific murine Cyp3a41 gene expression by growth and glucocorticoid hormones

✍ Scribed by Tsutomu Sakuma; Kaori Kitajima; Mie Nishiyama; Yusuke Endo; Kimiko Miyauchi; Kanokwan Jarukamjorn; Nobuo Nemoto


Book ID
116287794
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
148 KB
Volume
314
Category
Article
ISSN
0006-291X

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## Abstract The culture of fetal hepatocytes for 64 h in medium supplemented with 5 mM glucose, T3, insulin, and dexamethasone resulted in the coordinate precocious expression of malic enzyme mRNA, protein, and specific activity. T3 was the main inducer; meanwhile, insulin exerted a small synergist