✦ LIBER ✦
Cold-sensitivity of a double mutant strain combining two ribosomal mutations in the ascomycete Podospora anserina
✍ Scribed by Crouzet, M. ;Bégueret, J.
- Publisher
- Springer
- Year
- 1978
- Tongue
- English
- Weight
- 457 KB
- Volume
- 165
- Category
- Article
- ISSN
- 0026-8925
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✦ Synopsis
A double mutant strain combining two ribosomal mutations conferring resistance to cycloheximide exhibits a cold-sensitive phenotype. At low temperature the biosynthesis of the 60S subunit is impaired. Genetic analysis of cold-resistant revertants have shown that this double mutant strain can be used efficiently to isolate new ribosomal mutations.