DNA demethylation at specific CpG sites
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Ko Hashimoto; Richard O. C. Oreffo; Marc B. Gibson; Mary B. Goldring; Helmtrud I
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Article
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2009
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John Wiley and Sons
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English
β 553 KB
## Abstract ## Objective To determine whether changes in the DNA methylation status in the promoter region of the gene encoding interleukinβ1Ξ² (ILβ1Ξ²) account for expression of __IL1B__ messenger RNA (mRNA) after longβterm treatment of human articular chondrocytes with inflammatory cytokines. ##