Cold (0°C) ischaemic tolerance of latissimus dorsi free flaps in rats: A macroscopic and morphological study
✍ Scribed by Paul M. N. Werker; Moshe Kon; Colin J. Green; Patricia R. Fryer; Ralph J. P. M. Franken; Max L. E. Overgoor
- Publisher
- John Wiley and Sons
- Year
- 1994
- Tongue
- English
- Weight
- 549 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0738-1085
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✦ Synopsis
Abstract
The purpose of this study was to define the cold (0°C) ischaemic tolerance (CIT) of the latissimus dorsi free flap in inbred rats. Flaps were isolated, stored at 0°C for periods of time ranging from 0 to 120 hr and then revascularised and reperfused for 14 days. Thereafter the CIT was assessed macroscopically, and by light microscopy. Electron microscopy was performed in flaps after 0 and 24 hr of reperfusion following a cold ischaemic interval ranging from 0 to 120 hr. From this preliminary study, it was concluded that the CIT was 48‐72 hr.