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Colchicine Glycorandomization Influences Cytotoxicity and Mechanism of Action

✍ Scribed by Ahmed, Aqeel; Peters, Noël R.; Fitzgerald, Megan K.; Watson,, James A.; Hoffmann, F. Michael; Thorson, Jon S.


Book ID
121435595
Publisher
American Chemical Society
Year
2006
Tongue
English
Weight
53 KB
Volume
128
Category
Article
ISSN
0002-7863

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## Abstract Colchicine suppresses the development of carrageenan‐induced edema in the rat with a minimum effective oral dose of 6.0 mg/kg. The slope of the dose‐response regression line for colchicine differs significantly from that of indomethacin and phenylbutazone. Based on the dosages required