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Col2-GFP reporter mouse?A new tool to study skeletal development

โœ Scribed by Cho, Jae Y. ;Grant, T. Dawn ;Lunstrum, Gregory P. ;Horton, William A.


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
121 KB
Volume
106
Category
Article
ISSN
0148-7299

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Col2-GFP reporter marks chondrocyte line
โœ T. Dawn Grant; Jay Cho; Kiley S. Ariail; Nicole B. Weksler; Randall W. Smith; Wi ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 476 KB

Mice were generated in which a Col2-GFP transgene serves as a reporter for the chondrocyte lineage and for chondrogenesis in live embryos and newborn pups. Cells actively engaged in chondrogenesis were identified by confocal optical sectioning within their native environments in embryos and in thick