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COL1A1-PDGFB fusion in a pediatric Bednar tumor with 2 copies of a der(22)t(17;22)

✍ Scribed by Randall Craver; Tracy Dewenter; Nathalie Ebran; Florence Pedeutour


Book ID
113512912
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
124 KB
Volume
168
Category
Article
ISSN
0165-4608

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Malignant rhabdoid tumors are rare and aggressive neoplasms of childhood, occurring in the kidney or in various extrarenal locations. Most cytogenetic studies of these tumors have shown the frequent involvement of chromosome 22, including translocations and/or deletions, with a critical region for a