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Coinheritance of α-thalassemia-1 and hemoglobin E/β0-thalassemia: Practical implications for neonatal screening and genetic counseling

✍ Scribed by Lakshmanan Krishnamurti; David H.K. Chui; Michele Dallaire; Bonnie LeRoy; John S. Waye; John P. Perentesis


Book ID
117166246
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
134 KB
Volume
132
Category
Article
ISSN
1097-6833

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High frequency of deletional α-thalassem
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## Abstract Thalassemias are a group of genetic hemolytic disorders with varying phenotypes. In this study, the frequency of α globin gene deletions was studied in the β‐thalassemia trait, the mildest form of the disorder. Eleven out of 33 (33%) individuals were positive for α^−3.7 kb^ deletions. N