Cohesin-mediated chromatin interactions--into the third dimension of gene regulation

Cyclic AMP mediated GSTP1 gene activatio

Cyclic AMP mediated GSTP1 gene activation in tumor cells involves the interaction of activated CREB-1 with the GSTP1 CRE: A novel mechanism of cellular GSTP1 gene regulation

✍ Hui-Wen Lo; Francis Ali-Osman 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 English ⚖ 255 KB 👁 1 views

The human GSTP1 gene is frequently over-expressed in many human cancers and the expression increases with tumor progression and is associated with a more aggressive biology, poor patient survival, and resistance to therapy. The molecular regulation of the human GSTP1 gene during malignancy is, howev