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Cognitive Performance Correlates with Resting State Connectivity and is Effected by APOE Status

✍ Scribed by David T. Jones; Mary Machulda; Eric McDade; Prashanthi Vemuri; Guang Zeng; Steve Younkin; David S. Knopman; Bradley F. Boeve; Ronald C. Petersen; Clifford R. Jack


Book ID
118465842
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
178 KB
Volume
6
Category
Article
ISSN
1552-5260

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## Abstract ## Purpose: To identify the neural correlates of cognitive improvement in mild Alzheimer's disease (AD) subjects following 12 weeks of donepezil treatment. ## Materials and Methods: Resting‐state functional connectivity magnetic resonance imaging (R‐fMRI) was used to measure the hipp