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Cofilin-1 in the podocyte: a molecular switch for actin dynamics

✍ Scribed by Katja Berger; Marcus J. Moeller


Book ID
106555625
Publisher
Springer Netherlands
Year
2011
Tongue
English
Weight
192 KB
Volume
43
Category
Article
ISSN
0301-1623

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Cofilin, an actin-depolymerizing protein, is essential for the functional dynamics of the actin cytoskeleton and for cell viability. In unstimulated human peripheral blood T lymphocytes cofilin is phosphorylated and localized in the cytoplasm. Following co-stimulation through accessory receptors (e.