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Coffee protects against in vivo Abeta toxicity via activation of the skn-1 (Nrf2) detoxification pathway

✍ Scribed by Christopher D. Link; Vishantie Dostal; Christine M. Roberts


Book ID
118465954
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
121 KB
Volume
6
Category
Article
ISSN
1552-5260

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## Abstract The degeneration of dopaminergic neurons in the substantia nigra has been linked to the formation of the endogenous neurotoxin 5‐__S__‐cysteinyl‐dopamine. Sulforaphane (SFN), an isothiocyanate derived from the corresponding precursor glucosinolate found in cruciferous vegetables has bee