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Cofactor of BRCA1 modulates androgen-dependent transcription and alternative splicing

✍ Scribed by Jianlong Sun; Ashley L. Blair; Sarah E. Aiyar; Rong Li


Book ID
116698091
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
624 KB
Volume
107
Category
Article
ISSN
0960-0760

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BRCA1 is a tumour suppressor gene located on chromosome band 17q21. It is estimated that mutations in the BRCA1 gene account for approximately 45% of the breast cancer families and almost all of the breast/ovarian cancer families. We have used single strand conformation polymorphism analysis, direct