Ras/PI3Kinase/cofilin-independent activa
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Urban Sester; GuidoβH. Wabnitz; Henning Kirchgessner; Yvonne Samstag
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Article
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2007
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John Wiley and Sons
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English
β 359 KB
## Abstract T cell activation requires costimulation of TCR/CD3 plus accessory receptors (__e.g.__ CD28). A hallmark of costimulation is the dynamic reorganization of the actin cytoskeleton, important for receptor polarization in the immunological synapse. The classical model of T cell costimulatio