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Coexpression and characterization of the human large-conductance Ca2+-activated K+channel α

✍ Scribed by Jun Li; Chang-Lei Deng; Fang Gao; Jiu-Hua Cheng; Zhi-Bin Yu; Li Liu; Man-Jiang Xie


Publisher
Springer
Year
2009
Tongue
English
Weight
590 KB
Volume
331
Category
Article
ISSN
0300-8177

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The effect of pinacidil, an opener of ATP-sensitive K + (K ATP ) channels, on large-conductance Ca 2+ -activated K+ (BK Ca ) channels was investigated in cultured endothelial cells of human umbilical veins. In whole cell configuration, pinacidil (30 µM) increased the amplitude of K + outward current